Publications
14) "A Comprehensive Mathematical Model for Three-Body Binding Equilibria"
Douglass, E. F.; Miller, C. J.; Sparer, G.; Shapiro, H.; Spiegel, D. A.
J. Am. Chem. Soc., 2013, Just Accepted.
13) "Exterior Design: Strategies for Redecorating the Bacterial Surface with Small Molecules"
Gautam, S.; Gniadek, T. J.; Kim, T., Spiegel, D. A.
Trends in Biotechnology, 2013, 31, 258-267. ![]()
12) "The Unique Reactivity of N-phenacyl-derived Thiazolium Salts Toward Alpha-dicarbonyl Compounds"
Kim, T.; Spiegel, D. A.
Rejuvenation Research, 2012, (Epub)![]()
11) "Antibody-recruiting Molecules: An Emerging Paradigm for Engaging Immune Function in Treating Human Disease"
McEnaney, P. J.; Parker, C. G.; Zhang, A. X.; Spiegel, D. A.
ACS Chem. Biol., 2012, 1139-1151.![]()
10) "Wharton-fragmentation-based Approach to the Carbocyclic Core of the Phomoidrides"
Murphy, G. K.; Hama, N.; Bedermann, A.; Dong, P.; Schneider, C .M;, McMahon, T. C.; Tao, R. N.; Twenter, B. M.; Spiegel, D. A.; Wood, J. L.
Organic Letters, 2012, 4544-4547. ![]()
9) "Exploring Post-translational Arginine Modification Using Chemically Synthesized Methylglyoxal Hydroimidazolones"
Wang, T.; Kartika, R.; Spiegel, D. A.
J. Am. Chem. Soc., 2012, 8958–8967. ![]()
8) "Reprogramming Urokinase into an Antibody-Recruiting Anticancer Agent"
Jakobsche, C. E.; McEnaney, P. J.; Zhang, A. X.; Spiegel, D. A.
ACS Chem. Biol., 2012, 316–321. ![]()
7) "A Chemically Induced Vaccine Strategy for Prostate Cancer"
Dubrovska, A.; Kim, C.; Elliott, J.; Shen, W.; Kuo, T.-H.; Koo†, D.-I.; Li, C.; Tuntland, T.; Chang, J.; Groessl, T.; Wu, X.; Gorney, V.; Ramirez-Montagut, T.; Spiegel, D. A.; Cho, C. Y.; Schultz, P. G.
ACS Chem. Biol., 2011, 1223-1231. ![]()
6) "Synthetic Immunology to Engineer Human Immunity"
Spiegel, D. A.
Nature Chemical Biology 2010, 6, 871-872. ![]()
5) "A Biosynthetic Strategy for Re-engineering the S. aureus Cell Wall with Non-Native Small Molecules"
Nelson, J. W.; Chamessian, A. G.; McEnaney, P. J., Kazmierczak, B. I.; Spiegel, D. A.
ACS Chemical Biology 2010, 1147-1155. ![]()
4) "A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules"
Zhang, A. X.; Murelli, R. P.; Barinka, C.; Michel, J.; Cocleaza, A.; Jorgensen, W. L.; Lubkowski, J.; Spiegel, D. A.
J. Am. Chem. Soc. 2010, 132, 12711-12716.![]()
3) "Chemical Control over Immune Recognition: A Class of Antibody-Recruiting Small Molecules That Target Prostate Cancer"
Murelli, R. P.; Zhang, A. X.; Michel, J.; Jorgensen, W. L.; Spiegel, D. A.
J. Am. Chem. Soc. 2009, 131, 17090-17092. ![]()
2) "An Antibody-Recruiting Small Molecule That Targets HIV gp120"
Parker, C. G.; Domaoal, R. A.; Anderson, K. S.; Spiegel, D. A.
J. Am. Chem. Soc. 2009, 131, 16392-16394. ![]()
1) "Spatiotemporal Control over Molecular Delivery and Cellular Encapsulation from Electropolymerized Micro- and Nanopatterned Surfaces"
Stern E.; Jay, S. M.; Demento, S. L.; Murelli, R. P.; Reed, M. A.; Malinski, T.; Spiegel, D. A.; Mooney, D. J.; Fahmy, T. M.
Adv. Funct. Mater. 2009, 19, 2888-2895. ![]()

